急性脑梗死患者血清TNF-a和IL-6的表达及疏血通干预的临床意义
Journal of Yunnan University of Traditional Chinese Medicine(2013)
Abstract
目的研究急性脑梗塞患者血清肿瘤坏死因子(TNF-a)和血清白介素6(IL-6)水平及疏血通干预后的变化,探讨其神经保护机制和临床意义。方法用临床随机对照的观察方法,将56例急性脑梗死患者按随机数字表法将入院的急性脑梗死患者随机分为疏血通治疗者和灯盏细辛对照组。两组疗程均为14d。分别在治疗1d、3d、7d和14d检测血清TNF-a和IL-6含量。结果疏血通治疗组治疗后患者血清TNF-a和IL-6含量明显减少,与灯盏细辛对照组比较差异有显著性(P<0.05)。结论疏血通能减少血清TNF-a和IL-6含量含量来改善急性脑梗塞患者缺损的神经功能。
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Key words
Shuxuetong injection,TNF-a,IL-6,acute cerebral infarction
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