Synthesis of oligosaccharides on soluble high-molecular-weight branched polymers in combination with purification by nanofiltration.
ORGANIC LETTERS(2004)
Abstract
An efficient approach for polymer-supported oligosaccharide synthesis is described whereby branched and high-molecular-weight PEG derivatives are used in combination with purification by nanofiltration. This methodology was applied to the preparation of a tetraglucoside and the tumor-associated antigen Le(x).
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Key words
nanofiltration,nanotechnology
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