抗精子抗体与不育的相关性研究
Guangxi Medical Journal(2007)
Abstract
目的探讨抗精子抗体(AsAb)与不育是否具有相关性,为临床提供诊疗的依据。方法选择186对不育夫妇为不育组,62对已生育的健康夫妇为正常对照组,分别用金标免疫斑点法测定血清中的AsAb。结果不育组丈夫血清中AsAb阳性率高于正常对照组丈夫,差异有统计学意义(χ2=8.492,P=0.004)。不育组妇女血清中AsAb阳性率高于正常对照组妇女,差异有统计学意义(χ2=12.058,P=0.005)。不育组丈夫血清中的AsAb与不育组妻子血清中AsAb有关联性(χ2=8.091,P=0.004)。结论AsAb与不育具有相关性。对不育夫妇进行病因初筛时,有必要检测AsAb,AsAb阳性者要进行治疗。
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Key words
Infertile woman,Antisperm antibody,Immunogold-labeling method,Spouse
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