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含噻唑环的肽脱甲酰基酶抑制剂的设计与合成

YIN Ling,WANG Yingying,ZHAO Guangwang

Journal of Jining University（2012）

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Abstract
以丙二酸二乙酯为原料经过多步反应,设计并合成了6个含噻唑环的肽脱甲酰基酶(PDF)抑制剂,利用1H NMR和HR-MS表征了它们的结构.
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Key words
BB-3497,peptide deformylase,thiazole,synthesis,inhibitor
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