[Clinical analysis of 10 cases of olfactory neuroblastoma].

OBJECTIVE:To review the diagnosis, treatment and prognosis of olfactory neuroblastoma. METHODS:Clinical data were retrospectively reviewed in 10 cases of olfactory neuroblastoma admitted from 1998 to 2002, including data of transmission electron microscopic (TEM) observation in 4 cases. According to Kadish's classification, 2 cases were in stage A, 4 in stage B and 4 in stage C. Three patients were treated with surgery alone, 7 with combined surgery and radiation. RESULT:Among 10 cases, the overall 5-year survival rate was 60 %(6/10); 3 patients died from local recurrence, 1 lost follow-up. TEM demonstrated granules in the cytoplasm of 3 patients. CONCLUSION:The combined surgery and radiation can achieve excellent local control. Transmission electron microscope is important for its diagnosis.