Evaluation of pyrrolin-2-one derivatives synthesized by a new practical method as inhibitors of plasminogen activator inhibitor-1 (PAI-1).
Bioorganic & Medicinal Chemistry Letters(2010)
摘要
The synthesis and evaluation of a series of pyrrolin-2-ones derivatives as PAI-1 inhibitors are described.
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关键词
Plasminogen activator inhibitor-1,PAI-1 inhibitor,Antithrombotic agent,Pyrrolin-2-one
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