Relationship between nm23H1 genetic instability and clinical pathological characteristics in Chinese digestive system cancer patients.
World journal of gastroenterology(2008)
摘要
MSI and LOH may independently control the biological behaviors of digestive system cancers. MSI could serve as an early biological marker of digestive system cancers. Enhanced expression of nm23H1 protein could efficiently inhibit cancer metastasis and improve its prognosis. LOH mostly appears in late digestive system cancer.
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关键词
nm23H1,gastric cancer,colonic cancer,hepatocellular carcinoma,gallbladder carcinoma
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