Clinical trial of a new diuretic—MK-685
Irish Journal of Medical Science(2008)
Abstract
MK-685 (CsHI:ONTC1HC1), an as yet unnamed agent, is a new oral diuretic struc'turally unrelated to existing diuretics. In animals it increases the excretion of sodium withou:t increasing the excretion of potassium or chloride. In this paper we report the results of volumetric and biochemical studies in 15 subjects, 13 of whom had cardiac oedema.
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Key words
clinical trial,potassium
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