A Miniaturized Carbon Dioxide Gas Sensor Based on Sensing of pH-Sensitive Hydrogel Swelling with a Pressure Sensor

Biomedical Microdevices(2005)

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Abstract
A measurement concept has been realized for the detection of carbon dioxide, where the CO 2 induced pressure generation by an enclosed pH-sensitive hydrogel is measured with a micro pressure sensor. The application of the sensor is the quantification of the partial pressure of CO 2 (Pco 2 ) in the stomach as diagnosis for gastrointestinal ischemia. The principle is put to the proof by examining the sensor response to changes in Pco 2 . Furthermore, the response time, temperature-sensitivity and resolution are determined. The sensor responds well to changes in Pco 2 with a maximum pressure generation of 0.29× 10 5 Pa at 20 kPa CO 2 . The 90% response time varies between 1.5 and 4.5 minutes at 37 ∘ C. The sensor shows a linear temperature-sensitivity which can easily be compensated for, and enables detection of Pco 2 changes as small as 0.5 kPa CO 2 .
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Key words
CO2,Pco2,carbon dioxide,hydrogel,pH-sensitive,pressure,sensor
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