自组装寡肽分子T2的体外矿化研究
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi（2007）
Abstract
以两亲性肽(Peptide Amphiphile)分子为基础,设计、合成了可自组装呈纤维状的寡肽分子T2,并利用双扩散凝胶系统进行体外生物矿化研究。结果发现:T2可明显缩短羟基磷灰石沉淀体外形成的时间。经X线衍射(XRD)和扫描电镜(SEM)检测,获得的羟基磷灰石沉淀具有非晶质特点。分析结果认为:T2促进矿化的作用可能与其中引入的负电荷区域有关,其性能改进和矿化机理的阐明需要进一步研究。
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Key words
self-assembly oligopeptide biomineralization double-diffusion gel system
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