Clinical Trial Simulation—A Case Study Incorporating Efficacy and Tolerability Dose Response

Wayne Ewy,Peter Lockwood,Candace Bramson

Statistics for Biology and HealthDose Finding in Drug Development（2006）

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摘要

This case study is based on an early clinical development project we conducted. Details that identify the candidate compound have been obscured for confidentiality reasons, but the situation described is not uncommon in early clinical development.

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