Identification of an indole series of prostaglandin D2 receptor antagonists

Bioorganic & Medicinal Chemistry Letters（2006）

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摘要

A novel indole series of PGD2 receptor (DP receptor) antagonists are presented. Optimization led to the identification of the potent and selective DP receptor antagonists 35 and 36.

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关键词

Prostaglandin D2,PGD2,DP receptor antagonist,Indole

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