Therapeutic Effect(Observation) of Vitamin C Combined with Erythropoietin in the Patients of Renal Anemia

Journal of Liaoning Medical University(2009)

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Abstract
Objective To observe the efficiency of intravenous vitamin C combined with erythropoietin in the treatment of renal anemia. Methods 14 uremia patients in Haemodialysis center of the Luhe Hospital with serum ferritin(SF)800ng/ml and transferrin saturation(TSAT)50%were chosen.These patients received intravenous transfusion of vitamin C 1.0g added to 100ml 0.9% NS half an hour before the finish of the dialysis.The observation lasted 12 weeks.The changes of Hb,Hct,SF,and TSAT were determined before and after the treatment,using data before the treatment as control.Results Hb and Hct increased while SF and TSAT decreased significantly in statistics in these patients after 12 - week treatment,compared with data before the treatment(P0.01 ). Conclusions Combination of vitamin C and erythropoietin is effective in improving the Hb levels in the uremia patients receiving maintenance hemodialysis with iron overload.
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Key words
renal anemia,erythropoieti,vitamin C
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