Design, synthesis, and preliminary studies of the activity of novel derivatives of N-cinnamoyl-L-aspartic acid as inhibitors of aminopeptidase N/CD13.

Bioorganic & Medicinal Chemistry（2009）

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摘要

The compound 8c was built and docked into the active site of APN (PDB code: 2DQM) using Sybyl7.0. The docking result was showed by PyMOL.

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关键词

N-Cinnamoyl-l-aspartic acid derivatives,Synthesis,Aminopeptidase N inhibitors

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