Modulation of benzo[a]pyrene induced neurotoxicity in female mice actively immunized with a B[a]P-diphtheria toxoid conjugate.
Toxicology and Applied Pharmacology(2013)
Abstract
Benzo[a]pyrene (B[a]P) is a small molecular weight carcinogen and the prototype of polycyclic aromatic hydrocarbons (PAHs). While these compounds are primarily known for their carcinogenicity, B[a]P and its metabolites are also neurotoxic for mammalian species.
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Key words
B[a]P,B[a]P-BA,DT,PAHs,Cyp1a1,Cyp1b1,ip,SE,CFA,IFA,NMDA,MW,RT,n.s.
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