Search
ChatPaper
AI Writing
analysis
Analysis
编组
Open Data
more
More
RankingsMust ReadingJournal&ConferenceAI TRAI HistoryMaster Reading TreeXiaomai's Star TalentsTrajectoryTalentNDI TrackerOpenAI sign Language
VIPCreated with Sketch.

基因多态性对他莫昔芬治疗乳腺癌的影响与个体化用药进展

濮之晨,汪五三,徐喆, 陈群,胡骅, 吴敏,谢海棠

Anhui Medical and Pharmaceutical Journal（2013）

Cited 0|Views15
No score
Abstract
他莫昔芬(Tamoxifen)为人工合成的非胆固醇类抗雌激素药物,被广泛用于临床的雌激素受体(estrogen receptor,ER)阳性乳腺癌患者防治,有显著的个体差异.他莫昔芬经肝药酶CYP2D6、CYP3A4/5和SULT1A1等调节,这些基因的多态性现象是,导致临床治疗个体化差异的重要原因.该文就近年来药物基因多态性对他莫昔芬在乳腺癌治疗的作用与个体化用药进展情况综述.
More
Translated text
Key words
CYP3A4 /5,tamoxifen,gene polymorphism,CYP2D6,personalized medicine
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined