Septerine and septerphine are new alkaloids of Aconitum septentrionale

From the roots of Aconitum septentrionale Koelle we have isolated the new nor- and bisnorditerpenoid alkaloids septerine (1) and septefine (2), each containing a N-methylanthraniloyl fragment. Their structures have been established from IR-, mass-, and PMR-spectral results. Structure (1) for septerine has been confirmed by the formation of lycoctonine on its hydrolysis.