Thymidylate synthase but not excision repair cross-complementation group 1 tumor expression predicts outcome in patients with malignant pleural mesothelioma treated with pemetrexed-based chemotherapy.
Journal of Clinical Oncology（2010）
Abstract
In patients with MPM treated with P-based chemotherapy, low TS protein levels are predictive of improved TTP and OS. The role of TS assessment is worth of prospective validation in future studies on MPM.
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Key words
malignant pleural mesothelioma treated,tumor expression predicts,chemotherapy,cross-complementation,pemetrexed-based
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