NEW TARGETS OF MIR-29 IN CELL COMMUNICATION DURING LIVER FIBROGENESIS
Journal of Hepatology(2011)
摘要
Aims: MicroRNAs (miRNA) are small noncoding RNAs that regulate gene expression by targeting mRNAs through translational repression or RNA degradation. Since hepatic stellate cells (HSC) represent the central cell type of liver fibrogenesis, we have analysed the miRNA pattern in HSC and demonstrated recently, that miR-29a/b reduce collagen expression in HSC. In the present study, we identified additional targets of miR-29 and investigated the role of miR-29 in fibrogenic cell communication.
更多查看译文
关键词
cell communication
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要