Peptidomimetic inhibitors of bacterial peptide deformylase
Bioorganic & Medicinal Chemistry Letters（2011）
Abstract
A series of N-formyl hydroxylamine peptide deformylase inhibitors (I) containing a cyclic azaamino moiety between the P1′ and P3′ substituents are presented. Selected compounds display antibacterial activity against pathogens associated with respiratory tract infections with representative compounds showing excellent MICs against Haemophilus influenzae.
MoreTranslated text
Key words
Peptide deformylase,Peptidomimetic,Azapeptide,Antibacterial,Metalloprotease
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined