A Novel Monoclonal Stool Antigen Test For The Detection Of H. Pylori Before And After Eradication Therapy: A Prospective Study In Outpatients
GASTROENTEROLOGY(2003)
Abstract
All patients underwent four tissue biopsies for histology and one tissue biopsy for each urease test (CLO and Pronto), during the gastroscopy.Results were examined at 30-rain intervals for 2 consecutive hours.The two test results are presented below.Pronto and CLO sensitivity at 120 rain was 79 % and 76 % respectzvely, in patients under no antisecretory therapy and no upper GI truck hemorrhage.We found a linear correlation between the histology grading and Pronto graded chromatic index, regarding the stomach mucosal colonization density of Hp.[ Y= -0,12 +0,8SX (F1,101 = 104 p< 0,0001)].Conclusions:Both test results were comparable at two hours.However Pronto test surpasses CLO, because it becomes positive in 48% of patients at 30 rain, offering a sooner diagnosis, even with a single biopsy specimen.Additionally, Pronto correlates the chromatic grading with the stomach mucosal colonization density by Hp reliably, providing to clinicians a clear idea of what to be expected in the forthcoming histology.Last but not least, Pronto net price is remarkably lower than that of CLO.
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Key words
prospective study
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