Protein interactions implicated in neurotransmitter release

Oussama El Far,Vincent O'Connor,Thomas Dresbach,Lorenzo Pellegrini,William DeBello,Felix Schweizer,George Augustine,Christian Heuss,Theo Schäfer,Milton P. Charlton,Heinrich Betz

Journal of Physiology-Paris（1998）

引用 7|浏览11

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摘要

Biochemical evidence indicates that the exocytotic release of neurotransmitters involves both evolutionary conserved membrane proteins, the SNAREs, as well as ubiquitous cytosolic fusion proteins, NSF and SNAPs. We have analyzed the biochemical properties and the physiological effects of these proteins. Our data suggest models how NSF, SNAPs and SNAREs may function in neurotransmitter exocytosis.

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关键词

protein interactions,neurotransmitter release,SNAREs

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