West Nile And St. Louis Encephalitis Virus Antibody Seroconversion, Prevalence, And Persistence In Naturally Infected Pig-Tailed Macaques (Macaca Nemestrina)

Renee R Hukkanen,H Denny Liggitt,Stephen T Kelley,Richard Grant,David M Anderson,Roy A Hall,Robert B Tesh, Amelia P Travassos DaRosa,Helle Bielefeldt-Ohmann

CLINICAL AND VACCINE IMMUNOLOGY（2006）

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摘要

Pig-tailed macaques (Macaca nemestrina) naturally infected with West Nile virus were monitored from 1999 to 2005 to determine virus-specific antibody seroconversion, prevalence, and persistence. Antibodies persisted for up to 36 months, as detected by epitope-blocking enzyme-linked immunosorbent and hemagglutination inhibition assays. Exposure to cocirculating St. Louis encephalitis virus was evaluated by Western blotting and immunofluorescence assays.

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hemagglutination inhibition,assays,microbiology

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