Enhanced transbuccal salmon calcitonin (sCT) delivery: effect of chemical enhancers and electrical assistance on in vitro sCT buccal permeation.

Dong-Ho Oh,Kyeung-Hwa Chun,Sang-Ok Jeon,Jeong-Won Kang,Sangkil Lee

European Journal of Pharmaceutics and Biopharmaceutics（2011）

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摘要

The flux (Js) of sCT was increased by the aid of absorption enhancers and iontophoresis. However Js of transbuccal sCT was more enhanced by the combination of absorption enhancers and electrical assistance.

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关键词

Salmon calcitonin,Buccal delivery,Peptide delivery,Absorption enhancers,Iontophoresis,Electrical assistance

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