Analysis of effect of Low Molecular Heparin Ca combined with Danshen injection on COPD complicating with pulmonary heart disease in acute severe period

Objective It is to explore the effect of Low Molecular Heparin Ca(LMHCa) combined with DanShen injection on chronic obstructive pulmonary disease(COPD) complicating with pulmonary heart disease in acute severe period.Methods 87 patients were randomly divided into two groups.Both the groups were given normal treatment.The therapy group was added with LMHCa 5?000 IU once time every 12 hours by subcutaneous injection and Dan Shen injection 20mL+Normal saline 250 mL once time everyday by intravenous drip.One course of treatment was 7 days.Pulmonary average arterial pressure,arterial blood-gas analysis,blood coagulated and fibrinolysis indexes were determined before and after treatment and the effect was evaluated.Results Compared with those in the control group,the clinical efficiency was better,the declining degree of pulmonary average arterial pressure was lower,and rising degree of oxygen pressure of blood was better in the therapy group(P all0.05).There were significant differences in prothrombin time(PT) and thrombin time(TT) before and after treatment in the therapy group(P0.05).The differences were also significant between the control group and therapy group after treatment(P0.05).Conclusion LMHCa given by subcutaneous injection and Dan Shen injection by intravenous drip could improve low down pulmonary arterial pressure and improve pulmonary function.