Woman feels breast lump – surgeon cannot: the role of ultrasound in arbitration

European Journal of Cancer(2004)

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Abstract
The role of ultrasound scanning (USS) in patients complaining of a breast lump where the clinical examination (CE) is normal is not clearly defined. To determine this in greater detail, all patients complaining of a breast lump underwent CE. Where no lump could be found, but was still reported by the patient, an USS was performed. All lesions underwent biopsy and/or aspiration, as well as mammography in suspicious cases or those over 40 years of age. This cohort represented 5% of all referrals in the study period. Four hundred and twenty women were prospectively studied in this way. Median follow up is 3.4 years (range 2.5–4.2 years). Twenty two had solid lumps (of which 3 were cancers) and 48 had cysts. Ninteen patients re-presented with symptoms in the same breast (median time=12 months (range 4.5–20 months), all of which were imaged on USS: 15 cysts and 4 further cancers (3 in the same quadrant as the original lump, one contralateral) were identified. Women with symptomatic breast lumps and a normal CE can be considered a reliable indication that cancer is very unlikely to be present (negative predictive value=0.98). Ultrasound may be a suitable complimentary investigation, which will relieve symptoms in those with cysts and can detect small clinically – and sometimes mammographically – occult breast cancers.
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Key words
Breast cancer,Ultrasound,Clinical examination,Breast lump
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