Design, synthesis of novel peptidomimetic derivatives of 4-HPR for rhabdoid tumors

Bhaskar C. Das,Melissa E. Smith,Ganjam V. Kalpana

Bioorganic & Medicinal Chemistry Letters（2008）

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摘要

Novel peptidomimetic derivatives of 4-HPR with substitution of the alkene backbone with a rigid ring structure retains activity against rhabdoid tumor cells.

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关键词

Rhabdoid tumor,4-HPR,Cyclin D1,Retinoid

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