O.112 CpG island methylation of p16INK4A in odontogenic keratocyst

To evaluate peri-implant bone loss, the presence of peri-implantitis, aesthetic satisfaction, and quality of life in patients with implant-based prosthetic restorations using implants with or without smooth necks, placed in different bone positions.400 patients received 1,244 implants: 515 with smooth neck monitored over an average of 6.44 ± 2.55 years and 729 without smooth neck monitored over 5.61 ± 2.52 years. Radiographic bone loss, presence of periimplantitis, implant loss, quality of life (OHIP-14), and patient satisfaction with prosthetic esthetics were evaluated, comparing groups.120 implants developed peri-implantitis, 15 with a 2.5 mm smooth neck and 105 without smooth neck. Patients without smooth-necked implants showed a worse quality of life with statistically significant difference (p < 0.001). Patient satisfaction with prostheses was higher among the group without smooth neck.Implants with smooth polished necks would appear to suffer less bone loss and peri-implantitis, and lead to better patient quality of life. However, implants without smooth necks placed crestally led to higher patient satisfaction with aesthetics.