Transposition of IS1397 in the family Enterobacteriaceae and first characterization of ISKpn1, a new insertion sequence associated with Klebsiella pneumoniae palindromic units.
JOURNAL OF BACTERIOLOGY(2001)
Abstract
IS1397 and ISKpn1 are IS3 family members which are specifically inserted into the loop of palindromic units (PUs), IS1397 is shown to transpose into PUs with sequences close or identical to the Escherichia coli consensus, even in other enterobacteria (Salmonella enterica serovar Typhimurium, Klebsiella pneumoniae, and Klebsiella oxytoca), Moreover, we show that homologous intergenic regions containing PUs constitute IS1397 transpositional hot spots, despite bacterial interspersed mosaic element structures that differ among the three species. ISKpnl, described here for the first time, is specific for PUs from K, pneumoniae, in which we discovered it, A sequence comparison between the two insertion sequences allowed us to define a motif possibly accounting for their specificity.
MoreTranslated text
Key words
sequence alignment
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined