Criteria for the safety evaluation of flavoring substances: The Expert Panel of the Flavor and Extract Manufacturers Association

Food and Chemical Toxicology(2005)

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摘要
The current status of the GRAS evaluation program of flavoring substances operated by the Expert Panel of FEMA is discussed. The Panel maintains a rigorous rotating 10-year program of continuous review of scientific data related to the safety evaluation of flavoring substances. The Panel concluded a comprehensive review of the GRAS (GRASa) status of flavors in 1985 and began a second comprehensive review of the same substances and any recently GRAS materials in 1994. This second re-evaluation program of chemical groups of flavor ingredients, recognized as the GRAS reaffirmation (GRASr) program, is scheduled to be completed in 2005.
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ABS,ADH,ALD,AE,CYP450,CHO,CoA,CoE,CCK,DDA,DNA,DSB,EC,ECETOC,EFSA,EH,E. coli,EPA,F,FAA,FDA,FEMA,FSM,GSH,GST,GRAS,GRASa,GRASr,IARC,IOFI,i.p.,LD50,M,MLA,MRCA,NAS,NCI,NFC,NOAEL,NOEL,NR,NTP,MW,OECD,PADI,PCI,PPARα,PE,ppm,PTS,S. typhimurium,SCE,SCF,SLR,TAMDI
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