Criteria for the safety evaluation of flavoring substances: The Expert Panel of the Flavor and Extract Manufacturers Association
Food and Chemical Toxicology(2005)
摘要
The current status of the GRAS evaluation program of flavoring substances operated by the Expert Panel of FEMA is discussed. The Panel maintains a rigorous rotating 10-year program of continuous review of scientific data related to the safety evaluation of flavoring substances. The Panel concluded a comprehensive review of the GRAS (GRASa) status of flavors in 1985 and began a second comprehensive review of the same substances and any recently GRAS materials in 1994. This second re-evaluation program of chemical groups of flavor ingredients, recognized as the GRAS reaffirmation (GRASr) program, is scheduled to be completed in 2005.
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关键词
ABS,ADH,ALD,AE,CYP450,CHO,CoA,CoE,CCK,DDA,DNA,DSB,EC,ECETOC,EFSA,EH,E. coli,EPA,F,FAA,FDA,FEMA,FSM,GSH,GST,GRAS,GRASa,GRASr,IARC,IOFI,i.p.,LD50,M,MLA,MRCA,NAS,NCI,NFC,NOAEL,NOEL,NR,NTP,MW,OECD,PADI,PCI,PPARα,PE,ppm,PTS,S. typhimurium,SCE,SCF,SLR,TAMDI
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