Novel 3-phenylpropane-1,2-diamine derivates as inhibitors of aminopeptidase N (APN).

Luqing Shang,Qiang Wang,Hao Fang,Jiajia Mu,Xuejian Wang,Yumei Yuan,Binghe Wang,Wenfang Xu

Bioorganic & Medicinal Chemistry（2008）

引用 22|浏览5

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摘要

The most active compound 12i was built and docked into the active site of APN (PDB code: 2DQM) using Sybyl7.0. The docking result was showed by LIGPLOT.

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关键词

Aminopeptidase N inhibitor,3-Phenylpropane-1,2-diamine derivates,Synthesis

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