Derivatives of Natural Tetrapyrroles for Photodynamic Therapy, 4. Oxidative Degradation Studies: Direct Analysis and Determination of Ether and Ester Linkages in Porphyrin Dimers and Oligomers of Hematoporphyrin Derivative (HPD),

Nikolaus Risch,Ulrike Hesse, Andrea Josephs,Rainer Gauler

LIEBIGS ANNALEN（1996）

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摘要

Oxidative degradation studies of dimeric porphyrins provide valuable information about the individual linkages between the porphyrin units. MS and NMR data of the degradation products of hematoporphyrin derivative furnish unambiguous evidence of ester and ether linkages in the di- and oligomeric compounds of HPD.

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oxidative degradation,di- and oligomeric porphyrins,maleimides,hematoporphyrin derivative,photodynamic therapy

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