胃癌患者血清白介素-4和干扰素-γ变化
Journal of Huaihai Medicine（2012）
Abstract
目的 观察胃癌患者血清白介素-4(IL-4)和干扰素-γ(IFN-γ)含量的变化,以探讨胃癌患者Th1/Th2免疫漂移状态.方法 采用酶联免疫吸附测定法( ELISA)测定21例胃癌患者和17例浅表性胃炎患者血清IL-4及IFN-γ的含量.结果 2组患者血清IL-4及IFN-γ含量分别为(4.83±1.95)pg/ml和(309.74±101.9)pg/ml,浅表性胃炎患者血清IL-4及IFN-γ含量分别为(4.78±2.03) pg/ml和(316.78±100.02) pg/ml,2组比较,差异无显著性(P＞0.05).结论 胃癌患者系统性免疫无明显的Th1/Th2漂移现象.
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Key words
Interleukin-4,Interferon gamma,Stomach neoplasms,Immunological shift
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