Synthesis And Structure-Activity Relationship Of C-3 Quaternary Ammonium Cephalosporins Exhibiting Anti-Mrsa Activities
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS(1997)
摘要
A series of cephalosporins bearing C-3 quaternary ammonium groups were prepared and evaluated for their anti-MRSA activity. They exhibit good to excellent in vitro activity (MICs = 1-8 mu g/mL) against MRSA. (C) 1997 Elsevier Science Ltd.
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关键词
structure activity relationship
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