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低流量单肺通气对肺内分流和动脉氧分压的影响

The Journal of Practical Medicine(2013)

Cited 23|Views27
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Abstract
目的:观察低流量单肺通气对肺内分流和动脉氧分压的影响。方法:40例需单肺通气的择期肺癌手术患者,ASAⅠ或Ⅱ级,随机分为常流量组(A组)和低流量组(B组),每组20例。两组单肺通气前吸入高流量的氧气4L/min和1%安氟醚,10min后将A组氧气流量调为3L/min,B组调为1L/min,两组每60min给予高流量的新鲜气体4L/min吸入5min,手术结束前30min停止吸入安氟醚,恢复流量至4L/min。在单肺通气前(T0)及单肺通气后15(T1)、30(T2)、45(T3)、60(T4)min及恢复双肺通气30min(T5)时测定动脉及混合静脉血血气分析,记录pH、PaCO2、PaO2,计算肺内分流量(Qs/Qt)。结果:两组患者单肺通气各时点较双肺通气时Qs/Qt增加、PaO2下降,差异有统计学意义(P<0.01);两组间Qs/Qt、PaO2差异无统计学意义(P>0.05)。结论:低流量单肺通气对肺内分流和动脉氧分压无明显影响。
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Key words
Intrapulmonary shunt,Low flow anesthesia,Hypercapnia,Hypoxemia,One lung ventilation
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