The therapeutic effect of medical ozone on knee osteoarthritis

Objective To observe the therapeutic effect of medical ozone (O3) on knee osteoarthritis(OA).Methods Forty-eight OA patients were randomly divided into group A (control group) or group B(treatment group),with 24 patients in each group. The patients in group A were treated by intracavitary injection of sodium hyaluronate(SH) 20 mg once a week for five consecutive weeks;the patients in group B were treated by intracavitary injection of medical ozone(O3) 40ml(concentration 40uuuuuuuuuug/ ml).The VAS and therapeutic efficacy were compared before the treatment with after the treatment 1,2,3 months. Results The VAS showed significant statistic difference between the two groups before and after the treatment,and group B had a lower VAS than group A.Although knee joint function was improved more in group B,the total efficiency did not show difference in two groups.No obvious side effects were observed in all patients.Conclusion Medical ozone injected intracavitary can effectively relieve the joint pain in patients with knee osteoarthritis and improve the joint movable degree,with satisfied clinical therapeutic effect,low cost and no obvious side effects.