Some aspects of the history of membrane-damaging toxins
Medical Microbiology and Immunology(1996)
摘要
In this review the following topics are considered: (a) the character of biomedical research and how it has changed during the last six decades; (b) the early history of membrane-damaging toxins; (c) comparative toxinology as illustrated by similarity of the toxins of the brown recluse spider and the bacterial agent of peudotuberculosis, and by similarity of a toxin of a sea anemone and the thiol-activated membrane-damaging agents of bacteria; (d) examples of the diversity of membrane-damaging toxins; (e) cooperative or synergistic lytic systems; and (f) the outlook for the future.
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关键词
Biomedical Research, Early History, Bacterial Agent, Lytic System, Brown Recluse Spider
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