A novel function of botulinum toxin-associated proteins: HA proteins disrupt intestinal epithelial barrier to increase toxin absorption.

Yukako Fujinaga,T Matsumura,Ying Jin,Yuki Takegahara,Y Sugawara,Alberto Albanese, H Bigalke, Kimberly A Foster,M B Hallett,Joseph Jankovic,C Montecucco, Giampietro Schiavo

Toxicon（2009）

引用 25|浏览6

暂无评分

摘要

Food-borne botulinum neurotoxin (BoNT) in the gastrointestinal lumen must cross an epithelial barrier to reach peripheral nerves to mediate its toxicity. The detailed mechanism by which BoNT traverses this barrier remains unclear.

查看译文

关键词

Toxin,Hemagglutinin,Botulinum,Clostridium,Epithelial barrier,Caco-2

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要