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血清载脂蛋白E与脑梗死的关系研究

Journal of Medical Research(2013)

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Abstract
目的分析载脂蛋白E(ApoE)在脑梗死(cerebral infarction,CI)患者血清中的水平,探讨两者之间的关系。方法检测78例CI患者(CI组)和50例健康体检者(对照组)载脂蛋白E、总胆固醇(TC)、血尿酸(UA)水平,并进行统计学分析。结果 CI组ApoE、TC、UA水平显著高于对照组(P<0.01),诊断的敏感度和特异性分别为:84.6%和90.0%、47.4%和88.0%、59.0%和68.0%。结论血清载脂蛋白E与脑梗死关系密切,可能是其重要风险因子,对其具有一定的辅助诊断价值。
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Key words
ROC curve,Apolipoprotein E,Risk factor,Cerebral infarction
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