Synthesis, gene-silencing activity and nuclease resistance of 3'-3'-linked double short hairpin RNA.
Bioorganic & Medicinal Chemistry(2010)
Abstract
Short hairpin RNAs linked at their 3′ ends by glycerol show structure-dependent gene-silencing activity as well as higher exonuclease resistance and lower induction of interferon-α than siRNA or canonical shRNA.
MoreTranslated text
Key words
3′–3′-Linked double short hairpin RNA,Gene-silencing activity,Nuclease resistance,Innate immune response
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined