[Hepatitis B virus X protein induces malignant transformation tendency of Chang liver cells involving p16(INK4a) hypermethylation].
PubMed(2012)
Abstract
p16(INK4a) expression was repressed by HBx protein via DNA methylation of p16(INK4a), which can induce the malignant transformation tendency of Chang cells.
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Key words
chang liver cells,hepatitis,malignant transformation tendency
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