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Toll样受体与疟原虫侵染关系的研究进展

Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control(2012)

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Abstract
为深入了解疟原虫在侵染、繁殖过程中的分子机制,本综述从Toll样受体(Toll like receptor,TLR)与疟原虫的相互作用关系入手,探讨疟原虫在突破机体防御屏障后如何被TLR识别,并启动下游炎症反应的机制。其中涉及到的部分重要结构保守的生物大分子有成为新型药物靶分子的潜在特性。
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Key words
Invasion,Malaria,Malaria parasite,Toll like receptors
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