Development outline of Varicella Zoster Virus(VZV) and its vaccine

Varicella Zoster Virus( VZV) is the cause of chickenpox and shingles. VZV can cause chicken-pox in children and reactivation of VZV infection can cause shingles in adults. The incidence of chickenpox and shingles increases more in recent years. Effect of antivirus treatment is not good. That the molecular biological characteristics, animal model and immunity of the virus, the application of live attenuated vaccine, development of subunit are described and DNA vaccine also include it.