Parallel solution-phase synthesis of substituted 2-(1,2,4-triazol-3-yl)benzimidazoles
Tetrahedron Letters（2007）
Abstract
A solution-phase synthesis for the preparation of substituted 2-(1,2,4-triazol-3-yl)benzimidazoles from triazole aldehydes and ortho-phenylenediamines has been developed for the purpose of producing diverse lead generation libraries. Crude products were obtained and further purified by mass-guided preparative HPLC.
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Key words
Solution-phase parallel synthesis,1,2,4-Triazoles,Benzimidazoles
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