A study of rabbit plasma progressive antithrombinic activity during acute phase inflammatory reaction and in experimental nephrotic syndrome

1.1. The development of the progressive antithrombinic activity in rabbit plasma as a function of the level of the two α-macroglobulins in two experimental pathologies: acute phase inflammatory reaction and nephrotic syndrome, were studied.2.2. In the first case, the antithrombinic activity is a result of the increased biosynthesis of plasmatic antithrombins: antithrombin III, α1 antitrypsin and α macroglobulins.3.3. In the nephrotic syndrome, this activity follows the increase in the αM levels, the other antithrombins having been massively eliminated from the circulation in the urine.