Recombination in the alphaherpesvirus bovine herpesvirus 1.

Veterinary Microbiology(2006)

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摘要
Herpesviruses are DNA viruses characterized by a low rate of nucleotide substitution. Therefore, other mechanisms must be involved to their evolution, like recombination that can be seen as an essential evolutionary driving force of these viruses. Recombination contributes to the long-term evolution of alphaherpesviruses. It acts also to continuously create new alphaherpesvirus strains.
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关键词
Alphaherpesvirus,DNA,Replication,Recombination,Virulence,Vector,Vaccine
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