Hepatitis C Virus Infection of Neuroepithelioma Cell Lines

Nicola F. Fletcher,Jian Ping Yang,Michelle J. Farquhar,Ke Hu,Christopher Davis,Qiuchen He,Kimberly Dowd,Stuart C. Ray,Sophie E. Krieger,Johan Neyts,Thomas F. Baumert,Peter Balfe,Jane A. McKeating,Flossie Wong–Staal

Gastroenterology（2010）

引用 67|浏览32

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摘要

Conclusions Neuroepithelioma-derived cell lines express functional receptors that support HCV entry at levels comparable to those of hepatoma cells. HCV infection in vitro is not restricted to hepatic-derived cells, so HCV might infect cells of the CNS in vivo.

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关键词

OCLN,Neurotropism,Brain,Therapy,Replicon,Huh-7,VX-950

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