异甘草酸镁联合还原型谷胱甘肽治疗DILI疗效观察
China Tropical Medicine(2009)
Abstract
目的观察异甘草酸镁联合还原型谷胱甘肽治疗药物性肝损伤的临床疗效。方法选择我科2005年5月~2008年10月因药物性肝损伤住院患者84例,随机分为两组,每组42例。对照组:给予甘草酸二铵等治疗;治疗组:给予异甘草酸镁联合还原型谷胱甘肽治疗,疗程4周后将两组治疗效果进行比较。结果治疗组在临床症状改善及肝功能恢复方面优于对照组,两组存在显著性差异。结论异甘草酸镁联合还原型谷胱甘肽治疗药物性肝损伤疗效较好。
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Key words
Reduced glutathione,Magnesium isoglycyrrhizinate,Effects,Drug-induced liver injury
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