Species and drug resistance of pathogenic bacteria causing urinary tract infections in senile diabetics

OBJECTIVE To approach species and drug resistance of pathogenic bacteria causing the urinary tract infections in senile patients with diabetes mellitus(DM) so as to offer evidence for reasonable use of antibiotics.METHODS The bacterial culture of midstream urine was performed for 267 cases of diabetics with urinary tract infections.According to National Guide to Clinical Laboratory Procedures,the bacterial culture and the identification were performed by the routine methods.The drug susceptibility testings were performed by K-B methods recommended by CLSI.The testing results were assessed.RESULTS Among 267 strains of pathogenic bacteria,Escherichia coli(61.0%) rated the top one,K.peneumoniae(10.1%)rated the second,and Enterococcus faecalis(9.4%) ranked the third.The total detection rate of ESBLs-producing strains was 47.4%,the detection rate of the meticillin-resistant Staphylococci(MRS) was 41.4%.All the gram-negative bacilli were 100.0% sensitive to the carbapenems antibiotics,and all the gram-positive cocci were 100.0% sensitive to the glycopeptide antibiotics;the different species of bacteria varied in the drug resistance to other commonly used antibiotics.CONCLUSION The different species of the pathogens causing the urinary tract infections in senile diabetics vary in the drug resistance.It is recommended that the clinician should choose the susceptible drugs for anti-infection therapy based on the etiological detection and drug susceptibility testing results.