Saudi Arabian Sickle Cell Anemia.: A Molecular Approach

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES(1989)

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Annals of the New York Academy of SciencesVolume 565, Issue 1 p. 143-151 Saudi Arabian Sickle Cell Anemiaa A Molecular Approach BARBARA A. MILLER, BARBARA A. MILLER Department of Pediatric Hematoiogy/Oncology, The Milton S. Hershey Medical Center, P.O. Box 850, Hershey, Pennsylvania 17033.Search for more papers by this authorMOHAMMED SALAMEH, MOHAMMED SALAMEH Dhahran Health Center, Dhahran, Saudi Arabia, 31311.Search for more papers by this authorMOHAMMED AHMED, MOHAMMED AHMED Dhahran Health Center, Dhahran, Saudi Arabia, 31311.Search for more papers by this authorNANCY OLIVIERI, NANCY OLIVIERI Department of Medicine, Children's Hospital Medical Center, 300 Longwood Avenue, Boston, Massachusetts 02115.Search for more papers by this authorTITUS H. J. HUISMAN, TITUS H. J. HUISMAN Department of Cell and Molecular Biology, Medical College of Georgia, 1459 Laney Walker Boulevard, Augusta, Georgia 30912.Search for more papers by this authorSTUART H. ORKIN, STUART H. ORKIN Department of Medicine, Children's Hospital Medical Center, 300 Longwood Avenue, Boston, Massachusetts 02115.Search for more papers by this authorDAVID G. NATHAN, DAVID G. NATHAN Department of Medicine, Children's Hospital Medical Center, 300 Longwood Avenue, Boston, Massachusetts 02115.Search for more papers by this author BARBARA A. MILLER, BARBARA A. MILLER Department of Pediatric Hematoiogy/Oncology, The Milton S. Hershey Medical Center, P.O. Box 850, Hershey, Pennsylvania 17033.Search for more papers by this authorMOHAMMED SALAMEH, MOHAMMED SALAMEH Dhahran Health Center, Dhahran, Saudi Arabia, 31311.Search for more papers by this authorMOHAMMED AHMED, MOHAMMED AHMED Dhahran Health Center, Dhahran, Saudi Arabia, 31311.Search for more papers by this authorNANCY OLIVIERI, NANCY OLIVIERI Department of Medicine, Children's Hospital Medical Center, 300 Longwood Avenue, Boston, Massachusetts 02115.Search for more papers by this authorTITUS H. J. HUISMAN, TITUS H. J. HUISMAN Department of Cell and Molecular Biology, Medical College of Georgia, 1459 Laney Walker Boulevard, Augusta, Georgia 30912.Search for more papers by this authorSTUART H. ORKIN, STUART H. ORKIN Department of Medicine, Children's Hospital Medical Center, 300 Longwood Avenue, Boston, Massachusetts 02115.Search for more papers by this authorDAVID G. NATHAN, DAVID G. NATHAN Department of Medicine, Children's Hospital Medical Center, 300 Longwood Avenue, Boston, Massachusetts 02115.Search for more papers by this author First published: July 1989 https://doi.org/10.1111/j.1749-6632.1989.tb24161.xCitations: 8 a B.A.M. is the recipient of Clinical Investigation Award No. HL01947 from the National Institutes of Health. This work was also supported by grants no. HLB 15157, HLB 3226, and HLB 05168 from the National Institutes of Health, Bethesda, Maryland. S.H.O. is an Investigator of the Howard Hughes Medical Institute. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1 Perrine, R. P., M. J. Brown, J. B. Clego, D. J. Weatherall & A. May. 1972. Benign sickle-cell anemia. Lancet ii: 1163–1167. 2 Dagoy, R. H. 1959. Malaria in oases of eastern Saudi Arabia. Am. J. Trop. Med. Hyg. 8: 223–291. 3 Perrine, R. P., M. E. Pembrey, P. John, S. Perrine, & F. Shoup. 1978. Natural history of sickle cell anemia in Saudi Arabs. Ann. Intern. Med. 88: 1–6. 4 Pembrey, M. E., W. G. Wood, D. J. Weatherall & R. P. Perrine. 1978. 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Med. 317: 415–420. 31 Thein, S. L., J. S. Wainscoat, M. Sampietro, J. M. Old, D. Cappellini, G. Fiorelli, B. Modell & D. J. Weatherall. 1987. Association of thalassemia intermedia with a beta-globin gene haplotype. Br. J. Hematol. 65: 367–373. 32 Perrine, S., B. Miller, M. Greene, R. Cohen, D. Hurst, E. Vichinsky, R. De Palma S. Lovett, B. Lubin & D. Faller. 1987. A physiologic metabolite inhibits fetal globin switching in erythroid progenitors of neonates and HbSS infants. Blood 68(Suppl. 1): 150a. 33 Miller, B. A., S. P. Perrine, G. Antogenetti, D. H. Perlmutter, S. G. Emerson, C. Sieff & D. V. Faller. 1987. γ-Interferon alters globin gene expression in neonatal and adult erythroid cells. Blood 69: 1674–1681. Citing Literature Volume565, Issue1Sickle Cell DiseaseJuly 1989Pages 143-151 ReferencesRelatedInformation
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sickle,anemia<sup>a</sup>,cell
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